Supplemental Material


DHS to gene connections:

The allGeneCorrelations files can be a bit confusing so let me here explain. The "p-value" column in the files is just the proportion of random correlations that were less than the true measured correlation. To truly convert this to a p-value I would have to take 1 minus this value for just one of the tails of the distibution. Instead, I'm just leaving it this way, so you can tell whether the correlation is on the high end or the low end of the permutation distribution. I left it as .996/.998 so you can tell enriched from depleted. So, perhaps I'm wrong to label that column p-value. On the website, I just did the 1-p transformation, and then use color coding to show whether its enriched or depleted. For any connections with p-value < .05, you can download the file labeled p.05. This file contains permutation scores from 0 to .05, or from .95 to 1. Some people are interested in less strict connections; for this you can download the p.2 file.

Raw DHS and Expression Signal